10 Most Expensive Pharmaceutical Drugs in the US

Soliris (Eculizumab) - Used to treat rare blood disorders like paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).

Actimmune (Interferon gamma-1b) - Prescribed for treating chronic granulomatous disease and severe, malignant osteopetrosis.

Cinryze (C1 esterase inhibitor [human]) - Used to prevent hereditary angioedema attacks, Cinryze is a high-priced medication in the U.S. market.

Daraprim (Pyrimethamine) - Despite its relatively low production cost, Daraprim gained notoriety for its steep price increase.

Myalept (Metreleptin) - Prescribed for treating complications of leptin deficiency in patients with generalized lipodystrophy.

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Harvoni (Ledipasvir/sofosbuvir) - Used to treat chronic hepatitis C virus (HCV) infection, Harvoni's high cost places it among the most expensive pharmaceutical drugs.

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Chenodal (Chenodeoxycholic acid) - Prescribed for treating gallstones in patients with non-functioning gallbladders.

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Naglazyme (Galsulfase) - Used to treat mucopolysaccharidosis type VI (MPS VI), Naglazyme is one of the most expensive pharmaceutical drugs.

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Acthar (Repository corticotropin injection) - Despite being an old drug, Acthar gained attention for its high price tag.

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H.P. Acthar Gel (Repository corticotropin injection) - Similar to Acthar, H.P. Acthar Gel is used to treat various conditions.

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