The Bible: The New Testament references a woman who had hemorrhaged for 12 years.
Talmud: Hemophilia, a mostly inherited genetic disorder, was recognized in the ancient.
Alfredo Pavlovsky (1907–1984): A little over 20 years later in 1947, Argentinian physician Alfredo Pavlovsky.
Tsarevich Alexei (1904-1918): Princess Alice's daughter, Alexandra, married Nicholas II of Russia and became Empress.
Prince Leopold, Duke of Albany (1853–1884): Prince Leopold was born with hemophilia, which contributed to his death following.