Ganondorf: Ganon is a fictional character and the central antagonist of Nintendo's Legend of Zelda series.
Albert Wesker: Albert Wesker is one of the central characters in Capcom's Resident Evil series.
GLaDOS: GLaDOS is a fictional artificially intelligent computer system appearing in the video games Portal
Ridley: Ridley is a villain from the Metroid series and a character from the Super Smash Bros.
Handsome Jack: Handsome Jack is the main antagonist of both Borderlands 2 and Tales
Kefka Palazzo: Kefka Palazzo is a character in the Final Fantasy series of video games.
Dr. Eggman: Doctor Ivo "Eggman" Robotnik is a fictional video game character and the main antagonist of the Sonic the Hedgehog series, created by Sega.
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Bowser: Bowser is the main antagonist of the Mario Bros.
Sephiroth: Sephiroth is a fictional character and main antagonist in the role-playing video game Final Fantasy VII developed by Square.
Vaas Montenegro: Vaas Montenegro is the secondary antagonist of Far Cry 3, appearing as the main antagonist for the first half of its storyline.