Eddie LeBec: ‘Cheers’ (Jay Thomas) - If you don’t like kissing your on-screen wife, maybe don’t complain.
Edie Britt: ‘Desperate Housewives’ (Nicollette Sheridan) - Edie Britt was killed off in 2009, reportedly due to Sheridan's.
Professor Maximilian Arturo: ‘Sliders’ (John Rhys-Davies) - The Welsh actor regularly complained about the script for the '90s.
Prue: 'Charmed' (Shannen Doherty) - Doherty has had a reputation for being difficult dating back to 'Beverly Hills.
Marissa Cooper: 'The O.C.' (Mischa Barton) - Marissa Cooper dies in a devastating car crash in the third season.
Dr. Derek Shepherd: Grey’s Anatomy’ (Patrick Dempsey) - McDreamy was killed in a car crash at the end of season 11.
Dr. George O’Malley: ‘Grey’s Anatomy’ (T.R. Knight) - Knight's character was also killed off, though by heroically sacrificing.
Harrison Wright: Scandal' (Columbus Short) Shonda Rhimes' TV universe is once again more scandalous off-screen. Short.
Valerie Hogan: Valerie' (Valerie Harper) - In one of the most surprising TV exits ever, the eponymous star of the show was killed.
Charlie Harper: Two and a Half Men’ (Charlie Sheen) - The fastest way to get killed off a show is by making antisemitic.
Libby Smith and Ana Lucia Cortez: ‘Lost’ (Cynthia Watros and Michelle Rodriguez) The 2000s phenomenon had two short-tempered stars.
James Evans, Sr: Good Times’ (John Amos) - John Amos became disillusioned with the cheap humor of the show.
Charlie Pace: Lost' (Dominic Monaghan) - So much trouble in Hawaiian paradise! Monaghan's much-loved character.
Jason Gideo: Criminal Minds’ (Mandy Patinkin) - The actor was quite vocal about this role being his biggest mistake.