Top 10 Rarest Diseases in the World

Kuru: a remote region of New Guinea among the Fore tribe and closely related to mad cow disease, Kuru is caused by prions, which is a protein.

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Morgellons: is psychosomatic is Morgellons, which involves black hairs or strange fibers on or under the skin, accompanied by painful skin sensations.

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Parry–Romberg syndrome: Parry-Romberg syndrome typically affects girls under 15 years of age, where the random areas of the skin appear to shrink or degenerate.

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RPI Deficiency: RPI Deficiency has only three known cases historically, where the patients have a Ribose-5-phosphate isomerase deficiency.

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Hutchinson-Gilford Progeria Syndrome HGPS: simply as Progeria, this disease is caused by a fatal genetic mutation that results in rapid aging, beginning in early childhood.

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Epidermodysplasia verruciformis: is also called Treeman syndrome, which is a hereditary skin disorder characterized by an abnormal susceptibility to human.

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Microcephaly: This medical condition affects sufferers from birth or develops within the first few years of their life, caused by under-development.

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Fields’ Disease: Disease in the world, named after Welsh twin sisters Catherine and Kristie Fields, which means that Field’s Disease.

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Methemoglobinemia: Methemoglobinemia occurs when elevated levels of methemoglobin affect how oxygen and ferric iron act in the blood.

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Fibrodysplasia ossificans progressive – Stoneman’s Disease: is caused by a mutation in the body’s repair system that causes muscles, ligaments and tendons.

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